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Μultidisciplinary approach
stratification of patients with carotid artery disease

TAXINOMISIS is a European Commission funded research project which aims to develop a new approach for the stratification of carotid artery disease patients.
TAXINOMISIS takes bold step beyond the state of the art unwinding the pathobiology underlying symptomatic plaques, discriminating distinct disease mechanism-driven states and biomarkers, and developing a multiscale risk stratification model.
TAXINOMISIS will deliver, as a main outcome, a software platform, which can perform the risk stratification.

TAXINOMISIS innovation capacity

Purpose

Provide novel disease mechanism-based stratification for carotid artery disease patients to address the need for stratified and personalised therapeutic interventions in the current era.

Purpose

  • Investigate the causal relationship of the major pathways and factors identified in symptomatic carotid artery disease
  • Study disease phenotypes and disintegrate them into endotypes according to specific pathobiological mechanisms
  • Integrate a computational model and an agent based model of plaque progression in the risk stratification tool
  • Perform a test for determining the presence of single Nucleotide Polymorphisms and predicting drug response
  • Evaluate the risk model of carotid artery disease stratification in an observational multicentre clinical study
  • Present a cost-effectiveness analysis

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 755320.

Project News and Events

Newsletter

The overall purpose of TAXINOMISIS is to provide novel disease mechanism-based stratification for carotid artery disease patients to address the need for stratified and personalised therapeutic interventions in the current era.